Use of tazarotene foam for the treatment of acne vulgaris
نویسندگان
چکیده
Acne vulgaris is a common inflammatory chronic disease of the pilosebaceous unit. It often requires long-term treatment, resulting in increased demand for topical medications that are popular with patients in order to achieve long-term compliance. Tazarotene foam 0.1% is a novel formulation of tazarotene. We review efficacy and tolerability studies of the new formulation, and suggest a possible place for the product in the management of acne vulgaris.
منابع مشابه
Safety and efficacy of tazarotene foam for the treatment of acne vulgaris
BACKGROUND Tazarotene foam is the first topical retinoid foam approved for the treatment of acne vulgaris. OBJECTIVE To review the safety and efficacy studies of tazarotene foam in the treatment of moderate to severe acne. METHODS Five Phase I safety studies in normal controls are reviewed and two Phase III safety and efficacy studies in patients with moderate to severe acne are reviewed. ...
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Topical retinoids offer highly effective treatment for both inflammatory and non-inflammatory acne, with tazarotene demonstrating greater efficacy than other topical retinoids. A multicenter, double-blind, randomized, parallel-group trial has been performed to evaluate whether the adjunctive use of clindamycin/benzoyl peroxide could enhance the efficacy of tazarotene still further. Patients wit...
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BACKGROUND Tazarotene is a new 3rd generation topical acetylenic retinoid. It normalizes keratinocyte differentiation, reduces keratinocyte proliferation and decreases expression of inflammatory markers. Tazarotene was approved by U.S.F.D.A. in 1997 for acne vulgaris. OBJECTIVES To evaluate the efficacy and safety of topical tazarotene 0.1% cream in the treatment of facial acne. MATERIALS A...
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